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Part 3: Most people with chronic pain are told: “Inflammation is the problem.” But that’s only part of the story. Your symptoms aren’t random. They’re driven by underlying physiology. Your body is managing: • Immune system signaling • Inflammatory regulation • Gene expression And the JAK-STAT pathway directly impacts all of them. Here’s what’s happening: Inflammatory messengers called cytokines communicate with your cells. When a cytokine binds to a receptor, it activates proteins called JAKs, w
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