The use of abatacept as an initial biologic disease-modifying antirheumatic drug (bDMARD) for the treatment of patients with rheumatoid arthritis (RA) is associated with a slightly elevated risk for cancer overall, and in particular for nonmelanoma skin cancer, compared with the use of other bDMARDs, according to the results of a population-based, real-world cohort study published in …

Oct 23, 2024 · For patients with axial spondyloarthritis (axSpA) who experience extra musculoskeletal symptoms such as acute anterior uveitis, bimekizumab (BKZ) may offer protective benefits, according to study results published in Annals of the Rheumatic Diseases.. Researchers conducted a pooled analysis of data from the following phase 2b/3 trials: BE MOBILE 1 (ClinicalTrials.gov Identifier: NCT03928704 ...

Apr 19, 2024 · Gout is a type of inflammatory arthritis characterized by the deposition of monosodium urate crystals and the formation of tophi in tissues, typically in or around the joints. 1 Gout occurs more commonly in men compared with women 2 and “usually presents with sudden onset of severe pain, redness, and swelling of a single joint, most often in the feet, ankle, or knee,” said Rebecca ...

Nov 25, 2024 · The American College of Rheumatology (ACR) has released a summary of a new guideline for the screening, treatment, and management of lupus nephritis (LN), emphasizing prompt diagnosis, personalized treatment approaches, and …

Apr 6, 2022 · References. American College of Rheumatology & American Association of Hip and Knee Surgeons. 2022 American College of Rheumatology/American Association of Hip and Knee Surgeons guideline for the perioperative management of antirheumatic medication in patients with rheumatic diseases undergoing elective total hip or total knee arthroplasty: guideline summary.

Mar 5, 2024 · Throughout 2024, the United States Food and Drug Administration (FDA) approved new drugs for the treatment of osteoporosis, rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), giant cell arteritis, Duchenne muscular dystrophy (DMD), and certain cancers, while also expanding treatment indications for previously approved drugs.

Dec 20, 2018 · Before the use of methotrexate and targeted biologic disease-modifying antirheumatic drugs (DMARDs) became standard practice in rheumatoid arthritis (RA) treatment, renal complications were common in RA, with a 37% to 57% prevalence of chronic kidney disease (CKD) previously noted in this population. 1 Such issues have decreased considerably as use of the older DMARDs and the chronic use of ...

Nov 15, 2022 · History and Epidemiology. A typically uniarticular condition, hydroxyapatite (HA) crystal deposition disease (HADD) is marked by the presence of hydroxyapatite crystals in the periarticular soft tissues, especially the tendons 1.HA is a mineral found in normal bone, but when it builds up in and around the joints it can cause inflammation, tenderness, and pain.

Aug 10, 2022 · Ehlers-Danlos syndrome is a group of inherited connective tissue disorders that primarily affects the skin, joints, and blood vessel walls1 but can affect every organ system and result in significant morbidity and mortality. Typical clinical manifestations are skin hyperelasticity, hypermobility of joints, the fragility of blood vessels, and …

Aug 18, 2020 · The use of disease-modifying antirheumatic drugs (DMARDs) and the adoption of an early and aggressive treatment strategy have transformed the outcomes of patients with rheumatoid arthritis (RA).