MPR

Subcutaneous Lecanemab Starting Dose Under Review for Alzheimer Disease

Previously lecanemab was only approved as an SC injection for maintenance dosing, following an initial 18 month IV phase.
Heart

Innovations in cardiac device therapy in the era of advanced rhythm management: implantable defibrillators and conduction system pacing

Cardiac device therapy has significantly evolved since the introduction of the first implantable pacemaker and the subsequent ...
MPR

First Treatment for Menkes Disease: FDA Approves Copper Histidinate

Zycubo is a copper replacement therapy administered via subcutaneous injection to bypass impaired GI absorption in patients with Menkes disease.
MedPage Today

Subcutaneous ICD Ekes Out Favorable Safety Signals 8 Years Into PRAETORIAN Trial

Though the PRAETORIAN group was technically unable to prove that 8 years was enough to give a subcutaneous implantable cardioverter-defibrillator (ICD) an edge in safety, complication rates helped ...
MassDevice

Boston Scientific has positive ICD, Watchman FLX, AI data

The Emblem and Empower devices comprise the mCRM system. [Image from Boston Scientific] Boston Scientific (NYSE: BSX) + today shared new clinical data supporting multiple therapies at the Heart Rhythm ...
ahajournals.org

Device-Related Complications in Transvenous Versus Subcutaneous Defibrillator Therapy During Long-Term Follow-Up: The PRAETORIAN-XL Trial

The PRAETORIAN trial (A Prospective, Randomized Comparison of Subcutaneous and Transvenous Implantable Cardioverter Defibrillator Therapy) investigated the efficacy and safety of the subcutaneous ...
ahajournals.org

Subcutaneous Implantable Defibrillators in Young Patients: Arrhythmias, Complications, and Physical Activity

The safety of subcutaneous implantable cardioverter defibrillator (S-ICD) recipients who lead active lifestyles and engage in recreational sports is unknown. We aimed to evaluate the association ...
Frontiers

Clinical performance of subcutaneous vs. transvenous implantable defibrillator in patients with ischemic cardiomyopathy: data from Monaldi Rhythm Registry

Introduction: Subcutaneous ICD (S-ICD) is an alternative to a transvenous implantable cardioverter-defibrillator (TV-ICD) system in selected patients not in need of pacing or resynchronization.