Researchers have solved a mystery that has confounded scientists for 80 years: the crystal structure of the ...

A team of NYU chemists and physicists are using cutting-edge tools—holographic microscopy and super-resolution imaging—to ...

Can you imagine a life-saving molecule whose “twin” is a deadly poison? As surprising as it may seem, this chemical reality is known as “chirality”. Like a right hand and a left hand, two molecules ...

Recently, the team led by Chief Physician Quan Zhang and Associate Professor Feng Liu at Tianjin Medical University General Hospital systematically evaluated the genetic associations between type 2 ...

Molecular structure of tuberculosis efflux pump reveals how bacteria resist key antibiotic by Jeff Hansen, University of Alabama at Birmingham ...

The structure showed 12 transmembrane helices in two pseudo-symmetric bundles and two periplasmic subdomains. Experiments showed that the coiled-coil domain, whose predicted model extends from one of ...

Introduction Hemoglobinopathies are characterized by genetic alterations in the globin chain genes that lead to structural modifications in the hemoglobin molecule. Currently, more than 900 mutations ...

Linus Pauling, The Hemoglobin Molecule in Health and Disease, Proceedings of the American Philosophical Society, Vol. 96, No. 5 (Oct. 15, 1952), pp. 556-565 ...

Indeed, the molecular analysis of hemoglobin has been the testing ground for many contemporary ideas and concepts in biology, particularly the understanding of the crystallographic structure and ...

Scientists at the Novartis Institutes for Biomedical Research (NIBR) in Cambridge have discovered a small molecule that could be used as a therapy for sickle cell disease (SCD). The molecular glue ...

Bizarre Scheme. Perutz studied molecular structure by analyzing X-ray photographs of crystallized hemoglobin. Scattered and deflected by the atoms within, the X-rays form a pattern of light and ...

The designation hemoglobin Georgetown is in keeping with the recommendation that a new hemoglobin, before complete chemical analysis, be identified by the letter designation of the previously ...