A non-opioid painkiller from Vertex Pharmaceuticals could become a blockbuster, but questions remain on whether it will prove safe and effective for chronic pain.

Playing against Mississippi State is “like a root canal without novocaine,” Jon Rothstein ... Ok, enough with all the corny dental puns and references. Forgive me. It’s late.

In 1957, after a riot at the Missouri State Penitentiary left four men dead and 50 wounded, state lawmakers created a ...

“Too much novocaine around here,” quips a desperate Nuria to a ... Things come to a head, in a mild way, when one of her first dates turns up at the dental surgery and tells her he’s left his wife.

Lucas said he endured a dental procedure to repair a broken filling without anesthetic because the dentist’s hands were shaking so much he refused to allow him to give him a shot of novocaine.

Nathan Caine can’t afford to fumble this. Watch the Novocaine Big Game Spot for this upcoming film starring Jack Quaid, Amber Midthunder, Ray Nicholson, Betty Gabriel, Matt Walsh, Lou Beatty Jr., Evan ...

Jack Quaid is turning the table from his ’The Boys’ character in ’Novocaine,’ which is not for the faint of stomach.