TMC207 inhibits the proton pump of mycobacterial ATP synthase, a critical enzyme in the synthesis of ATP for Mycobacterium tuberculosis. Resistance is achieved through mutations at position 63 or ...

Found inside mitochondria, ATP synthase generates the energy storage molecule adenosine triphosphate, which the cells of all living things use for fuel. The enzyme generally looks similar in shape ...

The prize was for the determination of the detailed mechanism by which ATP shuttles energy. The enzyme which makes ATP is called ATP synthase, or ATPase, and sits on the mitochondria in animal cells ...

Naturally, since this process is essential for the functioning of any organism, ATP synthase has been major research subjects for many years. An analysis of the enzyme structure by Masasuke Yoshida ...

Mitochondrial genome contributes polypeptide subunits to the five enzyme complexes that comprise ... which is harnessed by the ATP synthase to drive the formation of ATP.

The prize was for the determination of the detailed mechanism by which ATP shuttles energy. The enzyme which makes ATP is called ATP synthase, or ATPase, and sits on the mitochondria in animal cells ...