AP2A1 could serve as a biomarker for aging and a target for therapies aimed at slowing down or even reversing the aging ...

ISM001-055 was shown to have attenuated cellular senescence through the suppression of various aging processes, thus showing potential as a senomorphic drug.

The key to reversing cellular aging may lie in a protein responsible for toggling cells between a "young" and an "old" state.

Our recent work indicates that cellular senescence is a major factor driving expression of IL-1α in vitro and in vivo . A similar relationship holds for epithelial derived IL-8 and stromal FGF2. Thus ...

A groundbreaking study led by researchers at Insilico Medicine has revealed the potential of TNIK inhibition as an innovative ...

Senescent cells stop dividing but don’t die, and cellular senescence has been implicated in the development of a wide range of chronic diseases and disease processes, including obesity ...

The Senescence Accelerated Mouse-Prone 8 (SAMP8) is a naturally occuring mouse line that displays a phenotype of accelerated aging. While maintaining an inbred AKR/J line in the early 1970's, ...

Topical ABT-263 effectively reduced several senescence markers in aged skin, preparing it for improved wound healing.

A groundbreaking study led by researchers at Insilico Medicine has revealed the potential of TNIK inhibition as an innovative anti-aging strategy ...