Turning genes on and off is like flipping a light switch, controlling whether genes in a cell are active. When a gene is ...

Most people recognize Alzheimer's from its devastating symptoms such as memory loss, while new drugs target pathological aspects of disease manifestations, such as plaques of amyloid proteins. Now a ...

Turning genes on and off is like flipping a light switch, controlling whether genes in a cell are active. When a gene is ...

A gene-editing tool that can turn genes on and off like a light switch has been developed. Turning a gene on means activating ...

A figure from the paper illustates a key finding of "compromised compartmentalization": chromatin that was locking genes down in health became more open in Alzheimer's, while chromatin that was open ...

Essentially all cells in an organism's body have the same genetic blueprint, or genome, but the set of genes that are actively expressed at any given time in a cell determines what type of cell it ...

Sex-biased gene expression in the body organs evolves rapidly, supporting a mosaic model of maleness and femaleness across tissues and thus challenging binary views of sex characteristics in mammals.

The ALBORADA Drug Discovery Institute, University of Cambridge, Cambridge, United Kingdom ...