"The fire is growing with a moderate rate of spread and structures are threatened," Cal Fire said as it issued evacuation orders.
Two new fires ignited in San Diego County on Tuesday, as firefighters continue fighting blazes further north in Los Angeles.
The Hughes Fire was first reported shortly after 10:30 a.m. along Lake Hughes Road, near Castaic Lake and the 5 Freeway, according to Cal Fire.
At least 27 people have died in the Eaton and Palisades fires, the Los Angeles County Medical Examiner said Thursday evening. Seventeen of the deaths are from the Eaton Fire in Altadena and 10 from the Palisades Fire, according to the medical examiner.
The bushfire started northwest of Downtown Los Angeles and spread from Los Angeles County to Ventura County and prompted evacuations.
The Los Angeles County Sheriff's Department said in an update Thursday that 18 people remain missing after the Southern California wildfires. Overall, authorities received a total of 43 missing persons reports related to the Eaton and Palisades fires. Of those, 12 were located safe.
A second day of windy and dry conditions is in store for Southern California. Winds have picked up and are expected to continue through Tuesday morning, raising the risk of new wildfires sparking.
The Los Angeles haven’t spread in nearly a week, but the return of the Santa Ana winds to full strength could cause problems.
Several counties in Southern California faced "critical" fire risks this week, according to an AccuWeather forecast.
Parched Southern California was forecast to face more dangerous winds on Wednesday but could get some badly needed rain this weekend, dampening the prospects of another round of killer wildfires.
Firefighters have battled multiple fires in Los Angeles and Ventura counties over the last few days. But after an epic dry streak, Southern California will get its first real rain of the winter this weekend.