A CBBL research team led by Professor Balachandran Manavalan from the Department of Integrative Biotechnology at Sungkyunkwan ...
Antivirulence drugs are a new type of therapeutic drug that target virulence factors, potentially revitalising the drug-development pipeline with new targets. As antivirulence drugs disarm the ...
Some pathogens use temperature as a trigger and activate virulence only after entering the warmer environment of a host. A research team from Ruhr University Bochum, Germany, and the University of ...
During the early stages of a pandemic, viruses tend to evolve in ways that enhance their ability to reproduce and spread, rather than to evade the host's immune system. The genetics and sex of the ...
The second class of TTSS-associated chaperones, which are the subject of this article, specifically and tightly associate with their cognate virulence factor. The interactions in these complexes are ...
Cryo-electron microscopy (cryo-EM) has heralded a structural biology breakthrough that advances our understanding of how Vibrio cholerae colonizes the human gut and causes often life-threatening ...
The emergence of new variants of concern (VOC) has slowed down progress against the COVID-19 pandemic in 3 ways: 1. by increasing the transmissibility of the virus and hence the reproduction number; 2 ...
Barcelona, 15 January 2026,- Cholera remains a major global public health challenge, with an estimated 1.3 to 4 million cases and tens of thousands of deaths reported worldwide each year. Caused by ...
Scientists have identified a new virulence gene from a whole genome analysis of Providencia rustigianii, which can cause severe food poisoning symptoms. Members of the team had previously reported ...
Pathogenic bacteria often delay the activation of their virulence program until they are inside the host. Researchers have identified a new mechanism that controls this process. Some pathogens use ...