Mammalian transmissible spongiform encephalopathy (prion) and amyloid diseases seem to involve the self-propagation of abnormal fibrillar or sub-fibrillar protein aggregates. Similar processes explain ...

Prions -- are they viruses, nucleic acids, or "infectious" proteins? This question has haunted the medical and research community for decades, and it still puzzles investigators who are trying to ...

Scientists have determined how a normal protein can be converted into a prion, an infectious agent that causes fatal brain diseases in humans and mammals. The finding, in mice, is expected to advance ...

Prions represent a new class of infectious agents which propagate on a protein-only level, not requiring agent-encoded nucleic acids. Newly emergent prion diseases such as bovine spongiform ...

The identification of a previously unknown malady in the Fore Tribe of Papua New Guinea drew international attention to the group of brainwasting diseases called transmissible spongiform ...

The public often thinks of medical devices as complicated constructs of metal, plastics and electronics, but the fact is that many medical devices are made from animal-derived materials as well. Some ...

Agents of transmissible spongiform encephalopathies (TSEs) usually enter the body via a peripheral route and replicate in lymphoreticular tissues before moving into the brain. Any impairment of the ...

Transmissible spongiform encephalopathy or prion disease is triggered by the conversion from cellular prion protein to pathogenic prion protein. Notably, C-transmembrane form of prion protein and ...

Prion diseases, also known as transmissible spongiform encephalopathies (TSEs) are dreaded neurological diseases with a progressive course, and are invariably fatal. They are caused by tiny particles ...

Researchers at the Cornell Wildlife Health Lab are leading interagency efforts to prevent the spread of chronic wasting disease in New York and in the United States. CWD is a transmissible spongiform ...

Among the animal spongiform encephalopathies -- scrapies, transmissible mink encephalopathy, and bovine spongiform encephalopathy (BSE) -- BSE is certainly the disease that has wreaked the most havoc ...

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