Mammalian transmissible spongiform encephalopathy (prion) and amyloid diseases seem to involve the self-propagation of abnormal fibrillar or sub-fibrillar protein aggregates. Similar processes explain ...

Agents of transmissible spongiform encephalopathies (TSEs) usually enter the body via a peripheral route and replicate in lymphoreticular tissues before moving into the brain. Any impairment of the ...

Prions represent a new class of infectious agents which propagate on a protein-only level, not requiring agent-encoded nucleic acids. Newly emergent prion diseases such as bovine spongiform ...

The identification of a previously unknown malady in the Fore Tribe of Papua New Guinea drew international attention to the group of brainwasting diseases called transmissible spongiform ...

The public often thinks of medical devices as complicated constructs of metal, plastics and electronics, but the fact is that many medical devices are made from animal-derived materials as well. Some ...

The barriers that keep people from getting chronic wasting disease from infected animals’ venison may not be as solid as ...

Transmissible spongiform encephalopathy or prion disease is triggered by the conversion from cellular prion protein to pathogenic prion protein. Notably, C-transmembrane form of prion protein and ...

In a new study, researchers from Case Western Reserve University School of Medicine have identified the structure of protein fibrils linked to a hereditary form of human prion disease. This insight, ...

Researchers at the Cornell Wildlife Health Lab are leading interagency efforts to prevent the spread of chronic wasting disease in New York and in the United States. CWD is a transmissible spongiform ...

One case of Bovine Spongiform Encephalopathy (BSE) has been detected in a cow on a farm in England. The animal died and has been removed from the farm in Somerset, according to the Animal and Plant ...