Transient receptor potential (TRP) channels constitute a large superfamily of non-selective cation channels that detect a wide array of physical and chemical stimuli. Mammalian genomes encode seven ...

The Jackson Laboratory has disclosed short transient receptor potential channel 3 (TRPC3) and short transient receptor potential channel 6 (TRPC6) antagonists reported to be useful for the treatment ...

Researchers found that a Transient Receptor Potential (TRP) A1 stimulant, 2-methylthiazoline (2MT), act as a potent insect repellent in Drosophila. 2MT induces aversive behaviors via olfactory, ...

Touch a hot plate and your hand flies back. While the response is almost instant, researchers are still working to better understand the molecular mechanisms behind these sensations of heat and pain.