The timely and accurate transcription of coding regions of the genome by RNA polymerase II (RNAPII) is crucial for the proper functioning of the cell 1. However, the DNA template is constantly exposed ...
Beyond its essential roles in ensuring faithful chromosome segregation and genomic stability, the human Smc5/6 complex acts as an antiviral factor. It binds to and impedes the transcription of ...
The binding of proteins to DNA is crucial for producing other proteins, ensuring that all the necessary processes in cells are performed, and for switching genes on or off. Proteins that bind to DNA ...
New tech reveals findings that address long-standing theories about how bacteria begin the process of making RNA from DNA. Every living cell transcribes DNA into RNA. This process begins when an ...