Dysregulated R-loops can cause stalled replication forks and telomere instability. However, how R-loops are recognized and regulated, is still not well understood, particularly at telomeres. In this ...
An RNA-based therapeutic approach led to transient activation of telomerase activity in a model of pulmonary fibrosis. A new report suggests that RNA-based human telomerase reverse transcriptase ...
There’s a new argument against “junk DNA.” In this microscope image, the ends of chromosomes are protected by specific DNA sequences called telomeres, visualized here in red. Credit: National ...