Censoring occurs when the failure times of some individuals within the observation sample cannot be observed. Censoring is often unavoidable in time-to-event studies. A patient in a clinical trial may ...
When interested in studying the effect of a treatment (or other exposure) on a time-to-event outcome, the most popular approach is to estimate survival probabilities using the Kaplan–Meier estimator.
Stakeholders asked the US Food and Drug Administration for more examples in comments on a recently issued guidance on the use of overall survival as an endpoint in oncology drug clinical trials. They ...