Sickle cell anemia (HbSS) is the homozygous dominant variant and the most common and severe form of the disease. Whereas patients who only inherited one gene encoding for abnormal HbS and a different ...

Recent therapies like hydroxyurea (Droxia, Bristol-Myers Squibb), the first FDA-approved drug for SCD in 1994, increase fetal hemoglobin (HbF), which, through unknown pathways, improves SCD symptoms ...

Two Pee Dee siblings are officially cured of sickle cell disease after more than a decade of living with the genetic blood ...

GREENVILLE, N.C. (WNCT) — WNCT’s Erin Jenkins sits down with a sickle cell disease survivor and a doctor to learn more about ...

AND017 is an investigational oral hypoxia-inducible factor prolyl hydroxylase inhibitor. The Food and Drug Administration has granted Orphan Drug designation to KIND Pharmaceutical’s AND017 for the ...

Researchers have found a link between the release from malformed red blood cells of the vital protein that carries oxygen and episodes of severe pain in people with sickle cell disease. The discovery ...

Sickle cell disease (SCD) is a genetic condition that affects more than 8 million people worldwide by altering the shape of oxygen-carrying red blood cells. Normally, red blood cells are shaped like ...

If you or someone you know has sickle cell disease (SCD), you may have heard of Lyfgenia, one of two gene therapies approved for this condition. Gene therapies are the only treatments for SCD that can ...

Please provide your email address to receive an email when new articles are posted on . Researchers observed what they called “alarming” underutilization of disease-modifying therapies for sickle cell ...

Today is World Sickle Cell Disease Day. The international awareness day is observed annually to increase public knowledge and an understanding of sickle cell disease and the challenges experienced by ...