Recent therapies like hydroxyurea (Droxia, Bristol-Myers Squibb), the first FDA-approved drug for SCD in 1994, increase fetal hemoglobin (HbF), which, through unknown pathways, improves SCD symptoms ...

Sickle cell anemia (HbSS) is the homozygous dominant variant and the most common and severe form of the disease. Whereas patients who only inherited one gene encoding for abnormal HbS and a different ...

Logan and Erin Dorsey, who had sickle cell anemia for 11 years, are now nurses at the University of Mississippi Medical Center, using their experience to help others. "Without God's grace, we wouldn't ...

Black History Month is poignant for one family after a man got a historic, innovative treatment at Children's Hospital of Philadelphia.

Sickle cell disease (SCD) is a group of genetic blood disorders. A person inherits SCD from their parents when they inherit two copies of the sickle cell gene, one from each parent. This hereditary ...

Sickle cell disease is inherited at birth when you receive related genes from both parents. One gene usually causes sickle cell trait (SCT), which often has no health problems. The main sickle cell ...

Sickle cell thalassemia occurs when you inherit both a sickle cell gene mutation and a thalassemia gene mutation. Symptoms are similar to other types of sickle cell disease but can vary depending on ...