TSAP6 (tumor suppressor-activated pathway 6), also known as Steap3, is a direct p53 transcriptional target gene. It regulates protein secretion, for example translationally controlled tumor protein ...
Autophagy and lysosomal pathways orchestrate unconventional secretion of Parkinson's disease protein
Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...
The system that allows the sharing of genetic material between bacteria – and therefore the spread of antibiotic resistance – has been uncovered by a team of scientists at Birkbeck, University of ...
Bacterial type III secretion machines have adapted to carry out numerous functions, ranging from locomotion to protein delivery into nucleated cells. One of the most intriguing issues is the source of ...
New research shows that a cellular program that causes aging can also bring unexpected benefits in the function of pancreatic beta cells and the production of insulin in mice and humans. The findings ...
Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...
Recently, "Long COVID" is becoming a significant medical issue worldwide. It refers to a variety of symptoms that persist over an extended period after the patient has recovered from a novel ...
The proteins responsible for the control of mucin secretions, a key component of protective mucus, have been established in two recent papers. Mucins, the vital proteins that compose the protective ...
Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...
Autophagy and lysosomal pathways orchestrate unconventional secretion of Parkinson’s disease protein
Oxidative stress induced by 6-OHDA stimulates autophagy flux, which enhances STX17-mediated autolysosome formation, leading to the degradation of autophagosomal contents. However, in response to ...
The system that allows the sharing of genetic material between bacteria -- and therefore the spread of antibiotic resistance -- has been uncovered by a team of scientists. Understanding the structure ...
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