Cells can spontaneously change shape even without external signals, but the underlying mechanisms behind this form of ...

How large, fully folded proteins can pass through cell membranes without destroying them has long been one of the open questions in cell biology. Using cryo-electron microscopy (cryo-EM), Leonid ...

J ohn Moult remembers the time he was floored by an algorithm. Moult, one of the organizers of the Critical Assessment of Protein Structure Prediction (CASP) competitions and a computational biologist ...

Every time a white blood cell engulfs a bacterium, a neuron extends a projection to connect with a neighboring cell, or when a cancer cell forcefully squeezes through tissue to spread, the cell must ...

Reactive oxygen species (ROS) produced naturally during cellular metabolism often cause oxidative damage to cells. However, ...

University of Pittsburgh postdoctoral researcher Mary Cundiff uses machine learning and single-cell genomics to study ...

Previously a professor at the Massachusetts Institute of Technology and a leader at the Broad Institute of M.I.T. and Harvard ...

Researchers discovered that a long-misunderstood protein plays a key role in helping chromosomes latch onto the right “tracks” during cell division. Instead of acting like a motor, it works more like ...

Full-body defense does not always look the way textbooks say it should. In planarian flatworms, a newly identified cell type ...

Scientists are exploring ways to mimic the origins of human life without two fundamental components: sperm and egg. They are coaxing clusters of stem cells – programmable cells that can transform into ...

Synthetic biology allows us to reuse, repurpose, and reconfigure biological systems to address society’s most pressing challenges. Developing biotechnologies in this way requires integrating concepts ...

Applications are invited for a fully funded 3.5 year PhD studentship to study the role of extracellular vesicles in cardiovascular disease, with a starting date of October 2026. Funding covers tuition ...