When the technique of pulsed-field gel electrophoresis (PFGE) was first described by David C. Schwartz and Charles R. Cantor almost a decade ago (Cell, 37:67-75, 1984), many molecular biologists ...

Pulsed-field gel electrophoresis (PFGE), or clamped homogeneous electrical field electrophoresis (CHEF), is a novel gel electrophoresis type for the separation of DNA macromolecules. This is ...

In this form of pulsed-field gel electrophoresis (transverse alternating field electrophoresis, also known as TAFE), electrodes are positioned on opposite sides of a vertical gel 1. The DNA moves ...

When constructing bacterial artificial chromosomes (BACs), researchers must verify that they successfully inserted their gene of interest. Because these insertions are large, scientists perform their ...

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What are the basic principles of electrophoresis? In electrophoresis, the substance that has to be separated is made to travel across a gel with a specific pore size using an electrical field. Also, ...