Scientists report that tiny tube-like protrusions called primary cilia on cells of the retinal pigment epithelium (RPE) -- a layer of cells in the back of the eye -- are essential for the survival of ...

A National Institutes of Health team has identified a compound already approved by the U.S. Food and Drug Administration that keeps light-sensitive photoreceptors alive in three models of Leber ...

The earliest eye damage from prion disease takes place in the cone photoreceptor cells, specifically in the cilia and the ribbon synapses, according to a new study of prion protein accumulation in the ...

The scientists focused on a component of the photoreceptors known as the connecting cilia, which links the outer, light-sensitive pigments of the cell to the machinery that converts that light into ...

Using confocal microscopy that can identify prion protein and various retinal proteins at the same time, the scientists found the earliest deposits of aggregated prion protein in cone photoreceptors ...

Jan. 2 (UPI) --Researchers made advances toward creating stem cell-derived retinal cells used to treat a leading cause of blindness, scientists at the National Eye Institute said. NEI scientists found ...

Scientists at the University of Michigan Medical School have discovered a gene called NPHP5 and found mutations in this gene that cause a rare genetic disease called Senior-Loken syndrome. Children ...

Prion diseases are a group of neurodegenerative disorders that are caused by the deposition of abnormally folded proteins in the brain. Prion diseases primarily involve the brain, but also can affect ...

Scientists at the National Eye Institute (NEI), part of the National Institutes of Health, report that tiny tube-like protrusions called primary cilia on cells of the retinal pigment epithelium (RPE) ...