In 2021, a research team discovered the insulin-inhibitory receptor 'Inceptor' and its role as a suppressor of the insulin signaling pathway. Now, the researchers have unlocked another, even more ...
Inceptor, like the M6PRs, is internalized from the plasma membrane by the adaptor protein AP-2 (ref. 29). CI-M6PR and CD-M6PR are bound by AP-1, which mediates intracellular budding of CCVs from the ...
Inceptor (encoded by Iir) is a novel receptor that inhibits insulin receptor and insulin-like growth factor signalling. A previous study showed that loss of inceptor from β-cells in lean ...
Three years ago, the inceptor protein was discovered and its role as an inhibitor of the insulin signaling pathway was described. Inceptor and the insulin receptor are located on the surface of beta ...
In 2021, a research team led by Prof. Heiko Lickert from Helmholtz Munich discovered the insulin-inhibitory receptor "Inceptor" and its role as a suppressor of the insulin signaling pathway. Now, the ...
Prof. Heiko Lickert is the director of the Institute of Diabetes and Regeneration Research at Helmholtz Munich, professor at the Technical University of Munich (TUM), and member of the German Center ...
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