A new imaging approach is shedding light on one of cell biology’s most elusive questions: how lipids are organized and sorted within membranes.
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Study maps how TRPM8 senses cold, pointing to a key lipid trigger
Researchers have captured the first cryo-electron microscopy snapshots of the cold-sensing ion channel TRPM8 in its open ...
A new imaging technique reveals lipids in cellular membranes and shows how they are organized at the nanoscale.
Biological membranes of cells and their subunits (organelles) are organized into tiny regions (nanodomains) made up of fats ...
Lipids are fatty molecules that play critical roles in cell function, including membrane structure, energy storage and nutrient absorption. Most lipids are made in a cell organelle called the ...
AD is associated with significant changes in genes related to neuroinflammation, and lipids are crucial in this metabolic dysregulation. Abnormal phospholipid accumulation in the brain not only ...
Every time a shuttle docks with the International Space Station (ISS), a delicate dance unfolds between the shuttle's docking system and its counterpart on the station. Thanks to international ...
Every time a shuttle docks with the International Space Station (ISS), a delicate dance unfolds between the shuttle's docking system and its counterpart on the station. Thanks to international ...
Lipid nanoparticles consist of spherical vesicles made of ionizable lipids with a positive charge at a low pH level, while being neutral at a physiological pH. Such a characteristic enables RNA ...
A new class of lipids improve the rates at which lipid nanoparticles (LNPs) successfully deliver RNA therapeutics and gene editing tools, promising to increase their effectiveness of such treatments.
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