DNA-protein crosslinks (DPCs) are bulky lesions formed when proteins become covalently attached to DNA, arising from endogenous metabolism, environmental agents or the action of specialised enzymes ...

Similar to the way DNA damage can contribute to human diseases such as cancer, it can also disrupt growth, development and ...

Cohesin is a protein that forms a ring-shaped complex which wraps and alters the DNA molecule shape. It moves through the DNA and creates specific loops in the genetic material which determine the ...

Our genetic heritage is not a blueprint or an algorithm, as many biologists have imagined, but something else entirely.

Progeria is a genetic condition that involves accelerated aging. Patients develop wrinkled skin, hair loss, and bone and joint stiffness from a very early age. One of the more unusual forms of this ...