An international collaboration steered by David Cortez, Richard N. Armstrong, Ph.D. Chair for Innovation in Biochemistry, explored how cells tolerate DNA damage and genome instability—and they arrived ...

A new study finds that when p53, one of the most important cancer-protecting genes, stops working, cells produce too much RNA ...

A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication. Led by Ichiro Hiratani and colleagues, the ...

If you are anything like us, whenever you plan a journey, you spend a remarkable amount of time thinking about the start and the middle. Is everything packed? What time should we leave? Will there be ...

The researchers have identified a previously unknown mechanism, potentially shedding additional light on how tumors develop.

DNA replication and repair mechanisms constitute the foundation of genomic integrity, ensuring that genetic information is faithfully duplicated and maintained across cell generations. Replication ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind DNA ...

Within the nucleus of every cell are long strings of DNA, the code that holds all the information needed to make and control every cell within a living organism. DNA, which stands for deoxyribonucleic ...

A molecular illustration of the crowded interior and cell envelope of Escherichia coli. (David S. Goodsell, The Scripps Research Institute) To replicate information, life usually has fairly ...

Researchers mapped RNA fragments embedded in human DNA, revealing a new genomic layer called the "ribome" that may shape gene ...