Cellular Metabolism Live-Cell Assays for Research and Drug Discovery Cellular energy production depends on mitochondrial integrity and function. Mitochondrial dysfunction has been shown to alter the ...

The increasing need to evaluate chemical safety without relying on animal models has driven the refinement and diversification of in vitro cytotoxicity assays. These tests involve exposing cultured ...

Cytotoxicity is a broad term that refers to the negative effects of chemical or environmental changes on cell health. Cells exposed to a cytotoxic stimulus may lose metabolic activity, experience ...

Measures of cell viability and cytotoxicity are essential for the development of new drug treatments for cancer. For a number of years, cell-based assays have been used to assess the impact of drugs ...

Intramuscular implantation assesses local tissue response to an implanted material for the ISO 10996-6 implantation test. However, manufacturers are on their own when it comes to how best to fulfill ...