A new analysis explores the genetic liability of psychiatric disorders using polygenic scores and recurrent copy number variants.

Human speech is a complex phenomenon engaging >72 muscles with synchronized control, modulated by the nervous system. Speech, the most common form of human communication, is naturally acquired by ...

The etiology of sporadic Parkinson’s disease (PD) is complex and multifactorial, shaped by a dynamic interplay between genetic susceptibility and environmental exposures 1,2,3. While the majority of ...

However, ES is not the first choice for detecting copy number variants (CNVs), which are typically deletions or duplications of DNA segments. CNVs cause a significant proportion of genetic disorders.

Copy number variants (CNVs) are increasingly recognized as clinically significant biomarkers across a wide range of tumor types, with emerging evidence supporting their role in prognosis, therapeutic ...

Copy number variation (CNV) refers to an increase or decrease in the number of copies of a DNA sequence in a genome, which can subsequently be implicit in promoting aberrant gene expression patterns ...