Reactive oxygen species (ROS) produced naturally during cellular metabolism often cause oxidative damage to cells. However, ...

An international research team led jointly by the University Medical Center Göttingen (UMG), the University of Göttingen and ...

The cells in human bodies are subject to both chemical and mechanical forces. But until recently, scientists have not understood much about how to manipulate the mechanical side of that equation. That ...

Cells manage a wide range of functions in their tiny package — growing, moving, housekeeping, and so on — and most of those functions require energy. But how do cells get this energy in the first ...

For the immune system to effectively combat pathogens, antibody responses must be precisely controlled. So-called follicular ...

A new study led by Marco Fumasoni, principal investigator at Fundação GIMM, shows that evolution can substantially reduce ...

The survival and suppressive function of regulatory T (Treg) cells rely on various intracellular metabolic and physiological processes. Our study demonstrates that Vps34 plays a critical role in ...

A first-in-human clinical trial of an immune rejuvenation therapy designed to restore the function of worn-out T cells is ...

B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME). Their anti-tumor functions include recognizing tumor-associated antigens, ...

Life and death are traditionally viewed as opposites. But the emergence of new multicellular life-forms from the cells of a dead organism introduces a “third state” that lies beyond the traditional ...

Among the body's most crucial protective features are the brain barrier systems, including the blood-brain and blood-cerebrospinal fluid (CSF) barriers. These barriers are made of highly specialized ...