The BCG (Bacillus Calmette–Guérin) vaccine is given intradermally and has variable efficacy against pulmonary tuberculosis, a highly contagious disease that is responsible for about 1.5 million deaths ...

Tuberculosis (TB) is an infectious condition that can be fatal without treatment. It occurs following infection with the bacterium species Mycobacterium tuberculosis. The Bacille Calmette-Guérin (BCG) ...

BCG therapy for NMIBC is associated with significant symptoms and side effects, but combining it with chemotherapy reduces these effects. BCG induction with maintenance is less toxic than induction ...

In March 2020, as the UK was preparing to go into lockdown, two new trials were posted on the clinicaltrials.gov database. The researchers were proposing that BCG, an old vaccine against tuberculosis ...

Imfinzi addition to BCG therapy significantly improved DFS in high-risk NMIBC patients, with a 32% reduction in DFS events. The study involved 1,018 patients, with three cohorts receiving different ...

Bladder cancer illustration The immunotherapy N-803 appears to boost innate immune memory and prolong the duration of response to therapy. Combination treatment with N-803, an investigational ...

Novel immunotherapies and chemotherapies hold promise as non-surgical salvage options. Recent advances in our understanding of systemic immunotherapy, however, have transformed the management of ...

Please provide your email address to receive an email when new articles are posted on . Bacillus Calmette-Guérin, or BCG, is highly effective at treating and preventing recurrence of early-stage ...

In a nested randomized controlled trial (RCT) published in eClinicalMedicine, researchers examined the effect of Bacillus Calmette-Guérin (BCG) vaccination on attenuating herpes labialis (cold sore) ...