The chemical ATP, adenosine triphosphate, is the fuel that powers all life. Despite ATP's central role, the structure of the enzyme generating ATP, F1Fo-ATP synthase, in mammals, including humans ...

Scientists have solved the structure of mitochondrial ATP synthase, an enzyme that makes ATP, adenosine triphosphate, the major energy source of cells. A team of scientists headed by Rosalind ...

How it works. ATP works by losing the endmost phosphate group when instructed to do so by an enzyme. This reaction releases a lot of energy, which the organism can then use to build proteins, contact ...

ATP synthase research has reached a milestone as single-molecule ... A rush of excitement ran through this field in 1997 when Noji et al. 1 discovered that ATP synthase is not just an enzyme, ...

ATP synthase is an important enzyme for the storage and release of energy in cells. Ion-mobility mass spectrometry has now been used to study its structure, revealing important mechanistic details ...

F ound inside mitochondria, ATP synthase generates the energy storage molecule adenosine triphosphate, which the cells of all living things use for fuel. The enzyme generally looks similar in shape ...

The discovery is remarkable, Lehmann says, not just for outlining a new role for the mitochondria beyond energy production, but also because it appears that ATP synthase's role in stem cell ...

A collaborative study from the University of Cologne has uncovered how a key mitochondrial protein, AIFM1 (Apoptosis-Inducing ...

The enzyme activity of mitochondrial ATP synthase was inhibited by CADD522 treatment. Differential scanning fluorimetry also demonstrated interaction of α subunits of the F1-ATP synthase to CADD522.

TMC207 inhibits the proton pump of mycobacterial ATP synthase, a critical enzyme in the synthesis of ATP for Mycobacterium tuberculosis. Pharmacokinetic properties.